Prof. Patrick Tighe


Prof. Patrick Tighe is Professor of Molecular Immunology within the Faculty of Medicine and Health Sciences at the University of Nottingham…


Prof. Patrick Tighe is Professor of Molecular Immunology within the Faculty of Medicine and Health Sciences at the University of Nottingham. Prof. Tighe has many years of experience in molecular cloning technologies, T cell receptor analysis, transcriptomics, fluorescent detection technologies and immunoassay technologies. He has a strong interest in laboratory automation, liquid handling robotics; lab-on-a-chip technologies; high-throughput ELISA and protein microarray analysis for applications in serology and intracellular signalling pathway analysis.  

 He has research interests in rare autoinflammatory conditions and systemic autoimmune diseases and spent many years investigating the molecular mechanisms associated with defects in the TNFR1 receptor, which gives rise to TNF-receptor-associated periodic syndrome (TRAPS). More recently, he has developed collaborative projects for the early diagnosis of cancer (autoantibody detection) and alternatives to TMA tumour staining (tumour antigen detection).